Multi-Channel Patterning of Antibodies on a Sensor Surface for Simultaneous Detection of Pathogens and Toxins
This poster describes the development of a micro-engineered, PDMS/PMMA composite patterning device for the flow immobilisation of up to 16 separate antibody stripes on a single sensor chip surface. Results for a preliminary six channel version of the device will be described with antibodies immobilised on a commercially available BIAcore (TM) surface plasmon resonance chip. Testing was carried out using a range of bacteria, viruses and proteins using a Light-Scattering SPR instrument. The ultimate aim is to use the device to pattern multiplex sensor chips with antibodies for application in the rapid detection of a range of pathogenic microorganisms and toxins in the field.
Item Type | Other |
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Uncontrolled Keywords | Microfluidics; Biosensor; Antibody; Patterning; Flow Immobilisation; SPR; BIAcore; Dstl |
Date Deposited | 26 Jul 2024 14:20 |
Last Modified | 26 Jul 2024 14:20 |
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picture_as_pdf - University of Hertfordshire - Biosensors 2010 poster.pdf
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- Centre for Engineering Research
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- Microfluidics and Microengineering
- Extracellular Vesicle Research Unit
- Centre for Research in Biodetection Technologies
- Centre for Hazard Detection and Protection Research
- School of Physics, Engineering & Computer Science
- Department of Engineering and Technology
- BioEngineering
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