Metabolism of captopril carboxyl ester derivatives for percutaneous absorption
Gullick, D.R., Ingram, M.J., Pugh, W.J., Cox, P.A., Gard, P., Smart, J.D. and Moss, G.P.
(2009)
Metabolism of captopril carboxyl ester derivatives for percutaneous absorption.
pp. 159-165.
ISSN 0022-3573
To determine the metabolism of captopril n-carboxyl derivatives and how this may impact on their use as transdermal prodrugs. The pharmacological activity of the ester derivatives was also characterised in order to compare the angiotensin converting enzyme inhibitory potency of the derivatives compared with the parent drug, captopril.
Item Type | Article |
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Date Deposited | 26 Jul 2024 15:39 |
Last Modified | 26 Jul 2024 15:39 |
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