Molecular similarity of MDR inhibitors
Zloh, Mire and Gibbons, S.
(2004)
Molecular similarity of MDR inhibitors.
pp. 37-47.
ISSN 1661-6596
The molecular similarity of multidrug resistance (MDR) inhibitors was evaluated using the point centred atom charge approach in an attempt to find some common features of structurally unrelated inhibitors. A series of inhibitors of bacterial MDR were studied and there is a high similarity between these in terms of their shape, presence and orientation of aromatic ring moieties. A comparison of the lipophilic properties of these molecules has also been conducted suggesting that this factor is important in MDR inhibition.
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Date Deposited | 26 Jul 2024 20:39 |
Last Modified | 26 Jul 2024 20:39 |
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