Methodologies for Assessing the Acceptability of Oral Formulations among children and older adults: A Systematic Review
Acceptability of medicinal products in children and older populations is pivotal in ensuring adherence and therapeutic outcomes. This review systematically identifies studies reporting on formulation aspects of oral medications that affect their acceptability in these patient groups. Particular emphasis is placed on the evaluation of the methodologies employed in the studies. Sixty-eight studies were included for analysis, with 51 (75%) in children and 17 (25%) in older populations. The studies evaluated a range of oral formulations; however, the methodologies used differ considerably in participants’ characteristics, study settings, tools, acceptability definitions and criteria. It is evident that there is a lack of standardisation in study design as well as the assessment methods used in assessing acceptability of medicines in children and older populations. This review presents a systematic analysis on methods employed for assessing acceptability of oral medicines in children and older adults, to provide insights and recommendations regarding the design of reliable instruments in future studies.
Item Type | Other |
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Subjects |
Pharmacology, Toxicology and Pharmaceutics(all) > Pharmacology Pharmacology, Toxicology and Pharmaceutics(all) > Drug Discovery |
Date Deposited | 26 Jul 2024 23:18 |
Last Modified | 26 Jul 2024 23:18 |
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picture_as_pdf - Ranmal_et_al_oral_formulations_published_version.pdf
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Read more research from the creator(s):
- Ranmal, Sejal
- O’Brien, Fiona
- Lopez, Felipe
- Ruiz, Fabrice
- Orlu, Mine
- Tuleu, Catherine
- Walsh, Jennifer
- Liu, Fang
Find work associated with the faculties and division(s):
- School of Life and Medical Sciences
- Department of Pharmacy, Pharmacology and Postgraduate Medicine
- Centre for Research into Topical Drug Delivery and Toxicology
- Pharmaceutics
- Pharmaceutical Analysis and Product Characterisation
- Bioadhesive Drug Delivery Group
- Department of Clinical and Pharmaceutical Sciences
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