Author
Number of items: 82.
Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin-1 and endothelial dysfunction in streptozotocin treated rats. (2018)
Yousif Shamsaldeen,
Rosemary Ugur,
Christopher Benham
and
Lisa Lione
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Altered detrusor contractility in MPTP-treated common marmosets with bladder hyperreflexia. (2017)
Sara Pritchard,
Atsuko Hikima,
Michael Jackson,
Lisa Lione,
Christopher Benham,
K. Ray Chaudhuri,
Sarah Rose,
Peter Jenner
and
Mahmoud Iravani
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Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives. (2016)
Jatinder Bassin,
Bhavani Anagani,
Christopher Benham,
Madhu Goyal,
Maryam Hashemian
and
Ute Gerhard
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Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies. (2016)
Yousif Shamsaldeen,
Louise MacKenzie,
Lisa Lione
and
Christopher Benham
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Synthesis and evaluation of chalcones and isobenzofuranones for their antimycobacterial activity. (2015)
Bhavani Anagani,
Jatinder Bassin,
Christopher Benham
and
Madhu Goyal
Selective inhibition of NADPH Oxidase reverses the over contraction of diabetic rat aorta. (2014)
Atif ur Rehman,
Elma Dugic,
Christopher Benham,
Lisa Lione
and
Louise Susan MacKenzie
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The spontaneous and neurogenic contractile responses of the isolated bladder smooth muscle are markedly enhanced in MPTP treated common marmoset (Callithrix jacchus). (2013)
Sara Pritchard,
Michael Jackson,
Lisa Lione,
Christopher Benham,
Sarah Rose,
Peter Jenner
and
Mahmoud M. Iravani
NADPH oxidase is the source of ROS in STZ rat aorta : use of the novel highly selective NOX inhibitor VAS2870. (2013)
Elma Dugic,
Yousif Shamsaldeen,
Christopher David Benham
and
Louise MacKenzie
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Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons. (2008)
Uma Anand,
William R Otto,
Daniel Sanchez-Herrera,
Paul Facer,
Yiangos Yiangou,
Yuri Korchev,
Rolfe Birch,
Christopher Benham,
Chas Bountra,
Iain P Chessell
and
Praveen Anand
Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette. (2008)
Daniel Sánchez,
Nick Johnson,
Chao Li,
Pavel Novak,
Johannes Rheinlaender,
Yanjun Zhang,
Uma Anand,
Praveen Anand,
Julia Gorelik,
Gregory I Frolenkov,
Christopher Benham,
Max Lab,
Victor P Ostanin,
Tilman E Schäffer,
David Klenerman
and
Yuri E Korchev
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. (2007)
Paul Facer,
Maria A Casula,
Graham D Smith,
Christopher D Benham,
Iain P Chessell,
Chas Bountra,
Marco Sinisi,
Rolfe Birch
and
Praveen Anand
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Localized and non-contact mechanical stimulation of dorsal root ganglion sensory neurons using scanning ion conductance microscopy. (2007)
Daniel Sánchez,
Uma Anand,
Julia Gorelik,
Christopher D Benham,
Chas Bountra,
Max Lab,
David Klenerman,
Rolfe Birch,
Praveen Anand
and
Yuri Korchev
Stretch-induced injury in organotypic hippocampal slice cultures reproduces in vivo post-traumatic neurodegeneration : role of glutamate receptors and voltage-dependent calcium channels. (2007)
Heather L Cater,
Daniel Gitterman,
Susan M Davis,
Christopher D Benham,
Barclay Morrison
and
Lars E Sundstrom
A hyperspectral fluorescence lifetime probe for skin cancer diagnosis. (2007)
P A A De Beule,
C Dunsby,
N P Galletly,
G W Stamp,
A C Chu,
U Anand,
P Anand,
C.D. Benham,
A Naylor
and
P M W French
Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurons. (2006)
K. Hill,
N. Tigue,
R.E. Kelsell,
C.D. Benham,
S. McNulty,
M. Schaefer
and
A.D. Randall
Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations. (2006)
G. Mukerji,
Y. Yiangou,
S. Corcoran,
I. S. Selmer,
G.D. Smith,
C.D. Benham,
C. Bountra,
S. K. Agarwal
and
P. Anand
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Sensing of lysophospholipids by TRPC5 calcium channel. (2006)
Philippa K Flemming,
Alexandra M Dedman,
Shang-Zhong Xu,
Jing Li,
Fanning Zeng,
Jacqueline Naylor,
Christopher D Benham,
Alan N Bateson,
Katsuhiko Muraki
and
David J Beech
TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated and functionally expressed in C13 microglia. (2006)
E. Fonfria,
C. Mattei,
K. Hill,
J.T. Brown,
A.D. Randall,
C.D. Benham,
S.D. Skaper,
C.A. Campbell,
B. Crook,
P.R. Murdoch,
J.M. Wilson,
F.P. Murio,
D. Owen,
P.L. Tilling
and
S. McNulty
Tissue distribution profiles of the human TRPM cation channel family. (2006)
E. Fonfria,
P. Murdock,
F.S. Cusdin,
C.D. Benham,
R.E. Kelsell
and
S. McNulty
An in-vitro model of traumatic brain injury utilising two-dimensional stretch of organotypic hippocampal slice cultures. (2006)
B. Morrison III,
H. Cater,
C.D. Benham
and
L. Sundstrom
Amyloid β-peptide(1-42) and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures. (2005)
E. Fonfria,
I.C.B. Marshall,
I. Boyfield,
S.D. Skaper,
J.P. Hughes,
D. Owen,
W. Zhang,
B.A. Miller,
C.D. Benham
and
S. McNulty
Simple recipe for blocking ion channels. (2005)
C.D. Benham
[3H]- resiniferatoxin autoradiography in the CNS of wild type and TRPV1 null mice defines TRPV1 (VR1) protein distribution. (2004)
J.C. Roberts,
J.B. Davis
and
C.D. Benham
Characterization of the human HCN1 subunit and its inhibition by capsazepine. (2004)
C.H. Gill,
S.A. Bates,
D. Owen,
P. Larkman,
W. Cairns,
S. Yusuf,
P. Murdock,
P. Strijbos,
A. Powell,
C.D. Benham
and
C.H. Davies
Flufenamic acid is a pH-dependent antagonist of TRPM2 channels. (2004)
K. Hill,
C.D. Benham,
S. McNulty
and
A.D. Randall
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase. (2004)
E. Fonfria,
I.C.B. Marshall,
C.D. Benham,
I. Boyfield,
J.D. Brown,
K. Hill,
J.P. Hughes,
R.E. Kelsell,
S.D. Skaper,
A.M. Scharenberg
and
S. McNulty
Capsazepine protects against neuronal injury caused by oxygen glucose deprivation by inhibiting Ih. (2003)
A. Ray,
C.D. Benham,
J.C. Roberts,
C.H. Gill,
C. Lanneau,
D.P. Gitterman,
M. Harries,
J.B. Davis
and
C.H. Davies
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Lactate and glucose as energy substrates during, and after, oxygen deprivation in rat hippocampal acute and cultured slices. (2003)
H. Cater,
A. Chandratheva,
C.D. Benham,
B. Morrison
and
L. Sundstrom
TRPV channels as temperature sensors. (2003)
C.D. Benham,
M.J. Gunthorpe
and
J.B. Davis
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Activation of TRPV4 channels (hVRL-2/mTrp12) by phorbol derivatives. (2002)
H. Watanabe,
J.B. Davis,
D. Smart,
J.C. Jerman,
G.D. Smith,
P. Hayes,
J. Vriens,
W. Cairns,
U. Wissenbach,
J. Prenen,
G.D. Flockerzi,
G. Droogmans,
C.D. Benham
and
B. Nilius
Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx. (2002)
A. Riccio,
C. Mattei,
R.E. Kelsell,
A.D. Medhurst,
A. R. Calver,
A.D. Randall,
J.B. Davis,
C.D. Benham
and
M. N. Pangalos
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Heat-evoked activation of TRPV4 channels in an HEK-293 cell expression system and in native mouse aorta endothelial cells. (2002)
H. Watanabe,
J. Vriens,
S. H. Suk,
C.D. Benham,
G. Droogmans
and
B. Nilius
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SB-334867-A antagonises orexin mediated excitation in the locus coeruleus. (2002)
E.M. Soffin,
M.L. Evans,
C.H. Gill,
M. Harries,
C.D. Benham
and
C.H. Davies
Vanilloid and TRP channels: a family of lipid gated cation channels. (2002)
C.D. Benham,
J.B. Davis
and
A.D. Randall
The diversity in the vanilloid receptor family of ion channels. (2002)
M.J. Gunthorpe,
C.D. Benham,
A.D. Randall
and
J.B. Davis
mRNA distribution analysis of TRPC family in human CNS and peripheral tissues. (2002)
A. Riccio,
A.D. Medhurst,
C. Mattei,
R.E. Kelsell,
A. R. Calver,
A.D. Randall,
C.D. Benham
and
M. N. Pangalos
A method for combining propidium iodide staining with immunohistochemistry. (2002)
C. Brana,
C.D. Benham
and
L. Sundstrom
Tetrodotoxin resistant sodium channels in pain. (2001)
C.D. Benham
The neuroprotective role of monocarboxylate transport inhibition during glucose deprivation in slice cultures of rat hippocampus. (2001)
H. Cater,
C.D. Benham
and
L. Sundstrom
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Cloning and functional expression of a human orthologue of the rat vanilloid receptor-1. (2000)
P. Hayes,
H.J. Meadows,
M.J. Gunthorpe,
M. Harries,
M. Duckworth,
W. Cairns,
D. C. Harrison,
K. Ellington,
R. Prinjha,
A. Barton,
A.D. Medhurst,
G.D. Smith,
S. Topp,
G. Sanger,
O. Jenkins,
C.D. Benham,
I. Gloger,
C. E. Clarke,
P. Murdock,
J. Terrett,
A. D. Randall,
I. S. Gloger
and
J. B. Davis
Caspase inhibitors are functionally neuroprotective against oxygen glucose deprivation induced CA1 death in organotypic hippocampal slices. (2000)
A. Ray,
D. Owen,
M.L. Evans,
J.B. Davis
and
C.D. Benham
Characterisation of SB-221420-A, a neuronal Ca and Na channel antagonist in experimental models of stroke. (2000)
C.A. Campbell,
F.C. Barone,
C.D. Benham,
S.J. Hadingham,
M. Harries,
J.M. Hills,
V.A. Lewis,
A.A. Parsons,
R.F. White
and
A.J. Hunter
Cloning, localisation and functional expression of the human ortholgue of the TREK-1 potassium channel. (2000)
H.J. Meadows,
C.D. Benham,
W. Cairns,
I. Gloger,
C. Jennings,
A.D. Medhurst,
P. Murdock
and
C.G. Chapman
Mutation of Histidine 286 of the human P2X4 receptor leads to loss of pH sensitivity. (2000)
C. Clarke,
C.D. Benham,
A. Bridges,
G. Sanger,
A. R. George
and
H.J. Meadows
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Rank-order inhibition by ω-conotoxins in human and animal autonomic nerve preparations. (2000)
G. Sanger,
E.S. Ellis,
M. Harries,
N.S. Tilford,
K.A. Wardle
and
C.D. Benham
Calpain activation and inhibition in organotypic rat hippocampal slice cultures deprived of oxygen and glucose. (1999)
C. Brana,
C.D. Benham
and
L. Sundstrom
Lack of effect of the novel anticonvulsant SB 204269 on voltage dependent currents in neurones cultured from rat hippocampus. (1999)
M. Caesar,
M.L. Evans
and
C.D. Benham
Orexin-A activates locus coeruleus cell firing and increases arousal in the rat. (1999)
J.J. Hagan,
R.A. Leslie,
S. Patel,
M.L. Evans,
T.A. Wattam,
S. Holmes,
C.D. Benham,
S.G. Taylor,
C. Routledge,
P. Hemmati,
R.P. Munton,
T.E. Ashmeade,
A.S. Shah,
J.P. Hatcher,
P.D. Hatcher,
D.N.C. Jones,
M.I. Smith,
D.C. Piper,
A.J. Hunter,
R.A. Porter
and
N. Upton
Recent advances in the molecular understanding of voltage gated Ca2+ channels. (1999)
C.D. Benham
and
A.D. Randall
Sensitivity to conotoxin block of splice variants of rat rbBII subunit of the N-type calcium channel co-expressed with different beta-subunits in Xenopus oocytes. (1999)
H.A. Meadows
and
C.D. Benham
SB 205384: A GABA-A receptor modulator with novel mechanism of action that shows subunit selectivity. (1998)
H.J. Meadows,
T.B. Blackburn,
D. Pritchett
and
C.D. Benham
Time course of the initial [Ca2+]i response to extracellular ATP in smooth muscle depends on [Ca2+]e and ATP concentration. (1998)
M.G. Mahoney,
L. L. Slakey,
C.D. Benham
and
D. J. Gross
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Furosemide inhibits regenerative cortical spreading depression in anaesthetised cats. (1997)
S.J. Read,
M.I. Smith,
C.D. Benham,
A.J. Hunter
and
A.A. Parsons
SB 205384 slows the decay of GABA-activated chloride currents in granule cells cultured from rat cerebellum. (1997)
H.J. Meadows,
M. Harries,
M. Thompson
and
C.D. Benham
The effects of SB 206284A, a novel neuronal Ca channel antagonist in models of cerebral ischaemia. (1997)
N. Wood,
F.C. Barone,
C.D. Benham,
T.H. Brown,
C.A. Campbell,
D.C. Cooper,
M.L. Evans,
G. Feuerstein,
T.C. Hamilton,
M. Harries,
P.D. King,
J.E. Meakin,
J.L. Murkitt,
S. Patel,
W.J. Price,
J.C. Roberts,
A.L. Rothaul,
N.A. Samson,
S.J. Smith
and
A.J. Hunter
The selective N type calcium channel antagonist omega conotoxin MVILA is neuroprotective against hypoxic neurodegeneration in organotypic hippocampal slice cultures. (1996)
A. K. Pringle,
L. Sim,
J. Kennedy,
G. J. C. Wilde,
C.D. Benham,
F. Iannotti
and
L. Sundstrom
SB 201823-A antagonises calcium currents in central neurons and reduces the effects of focal ischaemia in rats and mice. (1995)
F.C. Barone,
P. G. Lysko,
W.J. Price,
G. Feuerstein,
C.D. Benham,
D. C. Harrison,
M. Harries,
S. J. Bailey
and
A.J. Hunter
SB 201823-A, A neuronal Ca antagonist is neuroprotective in two models of cerebral ischaemia. (1993)
C.D. Benham,
T.H. Brown,
D.C. Cooper,
M.L. Evans,
M. Harries,
H.J. Herdon,
J.E. Meakin,
K.L. Murkitt,
S. Patel,
J.C. Roberts,
A.L. Rothaul,
S.J. Smith,
N. Wood
and
A.J. Hunter
Specific induction of intracellular calcium oscillations by complement membrane attack on oligodendroglia. (1993)
A. Wood,
M. Wing,
C.D. Benham
and
D. A. S. Compston
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ATP joins the fast lane. (1992)
C.D. Benham
Calcium Efflux mechanisms following depolarisation evoked calcium transients in cultured rat sensory neurones. (1992)
C.D. Benham,
M.L. Evans
and
C.J. McBain
Calcium influx stimulated by activation of ATP receptors on sensory neurons from rat dorsal root ganglia. (1991)
M.M. Bouvier,
M.L. Evans
and
C.D. Benham
Changes in cytoplasmic calcium induced by purinergic P2X receptor activation in vascular smooth muscle cells and sensory neurons. (1991)
C.D. Benham,
M.M. Bouvier
and
M.L. Evans
ATP gated channels in vascular smooth muscle cells. (1990)
C.D. Benham
Isolation of potassium, chloride and non selective cation conductances activated by noradrenaline in rabbit ear artery cells. (1990)
T. Amedee,
C.D. Benham,
T.B. Bolton,
N.G. Byrne
and
W.A. Large
SK&F 96365, a novel inhibitor of receptor mediated calcium entry. (1990)
J. E. Merritt,
P. A. Armstrong,
C.D. Benham,
T. J. Hallam,
R. J. Jacob,
A. Jaxa-Chamiec,
B. K. Leigh,
S.A. McCarthy,
K.E. Moores
and
T. J. Rink
ATP-activated channels gate calcium entry in single smooth muscle cells dissociated from rabbit ear artery. (1989)
C.D. Benham
Alterations in [Ca2+] mediated by sodium-calcium exchange in smooth muscle cells isolated from the guinea-pig ureter. (1989)
C.D. Benham
and
P.I. Aaronson
Voltage-gated and agonist mediated rises in intracellular Ca in rat clonal pituitary cells (GH3) held under voltage clamp. (1989)
C.D. Benham
Control of secretion in anterior pituitary cells - Linking ion channels, messengers and exocytosis. (1988)
W.T. Mason,
S.R. Rawlings,
P. Cobbett,
S.K. Sikdar,
R. Zorec,
S.N. Akerman,
C.D. Benham,
M. Berridge,
T. Cheek
and
R.B. Moreton
Noradrenaline modulation of calcium channels in single smooth muscle cells from rabbit ear artery. (1988)
C.D. Benham
and
R.W. Tsien
Action of extracellular adenosine triphoshate in single smooth muscle cells dispersed from the rabbit ear artery. (1987)
C.D. Benham,
T.B. Bolton,
N.G. Byrne
and
W.A. Large
Inward rectification in freshly isolated single smooth muscle cells of the rabbit jejunum. (1987)
C.D. Benham,
T.B. Bolton,
J.S. Denbigh
and
R.J. Lang
Two types of calcium channels in single smooth muscle cells from rabbit ear artery - studied with whole cell and single channel recordings. (1987)
C.D. Benham,
P. Hess
and
R.W. Tsien
A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle. (1987)
C.D. Benham
and
R.W. Tsien
Calcium activated K-channels in single dispersed smooth muscle cells or rabbit jejunum and guinea-pig mesenteric artery. (1986)
C.D. Benham,
T.B. Bolton,
R.J. Lang
and
T. Takewaki
Patch and whole cell voltage-clamp studies on single smooth muscle cells. Cellular Calcium Control Mechanisms. (1986)
T.B. Bolton,
R.J. Lang,
T. Takewaki
and
C.D. Benham
Spontaneous transient outward currents in single visceral and vascular smooth muscle cells of rabbit. (1986)
C.D. Benham
and
T.B. Bolton
Acetylcholine activates a non-specific inward current in single mammalian smooth muscle cells. (1985)
C.D. Benham,
T.B. Bolton
and
R.J. Lang
Patch and whole cell voltage-clamp of single mammalian visceral and vascular smooth muscle cells. (1985)
T.B. Bolton,
R.J. Lang,
T. Takewaki
and
C.D. Benham
The mechanism of action of Ba2+ and TEA on single Ca2+-activated K+-channels in arterial and intestinal smooth muscle cell membranes. (1985)
C.D. Benham,
T.B. Bolton,
R.J. Lang
and
T. Takewaki
Patch-clamp studies of slow potential sensitive potassium channels in longitudinal smooth muscle cells of rabbit. (1983)
C.D. Benham
and
T.B. Bolton